Recombinant Bovine Interleukin 17A
Cat.No. : | IL17A-236B |
Product Overview : | Recombinant Bovine IL-17A was expressed inYeast. MW= 17.4 kDa (132 aa). |
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Species : | Bovine |
Source : | Yeast |
Tag : | Non |
Description : | Interleukin-17A is a protein that in humans is encoded by the IL17A gene. The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. |
Formulation/ Reconstitution : | Lyophilized. Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein. |
Purification : | Ion-exchange chromatography. |
Purity : | >95% as visualized by SDS-PAGE analysis. |
Amino Acid Sequence : | KAGVIIPQSP GCPPTEDKNF PQHVRVNLNI VNRSTNSRRP TDYHKRSTSP WTLHRNEDPE RYPSVIWEAK CSHSGCINAE GKVDHHMNSV TIQQEILVLR RESQHCPHSF RLEKMLVAVG CTCVTPIVRH LA. |
Bioactivity : | In testing. |
Stability And Storage : | Stable for up to twelve months from date of receipt at -20°C. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles. |
Gene Name | IL17A interleukin 17A [ Bos taurus ] |
Synonyms | interleukin 17A; IL17A; IL17; IL-17; interleukin-17A; IL-17A; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8) |
Gene ID | 282863 |
mRNA Refseq | NM_001008412.1 |
Protein Refseq | NP_001008412.1 |
UniProt ID | Q687Y7 |
Chromosome Location | 23 |
Pathway | Cytokine-cytokine receptor interaction |
Function | cytokine activity |
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IL17A-588M | Active Recombinant Mouse Interleukin 17A, MIgG2a Fc-tagged, mutant | +Inquiry |
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◆ Cell & Tissue Lysates | ||
IL17A-001HCL | Recombinant Human IL17A cell lysate | +Inquiry |
Not For Human Consumption!
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