Recombinant Active S. alpha HLY protein

• Cat.No.: HLY-01S
• Product Overview: Recombinant Active S. alpha HLY protein without tag was expressed in E. coli.

Specification

• Description: Staphylococcus aureus alpha Hemolysin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. The toxin self-assembles to form first, a nonlytic oligomeric intermediate, and then, a mushroom-shaped homoheptamer structure. Heptamer oligomerization and pore formation is required for lytic activity.
• Source: E. coli
• Species: S. alpha
• Form: Liquid
• Bio-activity: Hemolysin is active in functional lysis assays with rabbit red blood cells. EC50 ~0.015 μg/mL.
• Molecular Mass: 33 kDa
• Endotoxin: 5.165 Eu/mg
• Purity: > 80% SDS-PAGE
• Applications: WB, Functional Studies, SDS-PAGE, ELISA
• Storage: Store at -80 centigrade.
• Storage Buffer: Constituents: PBS, 20% Glycerol (glycerin, glycerine)
  This product is an active protein and may elicit a biological response in vivo, handle with caution.
• Shipping: Shipped at 4 centigrade.
• Official Symbol: HLY
• Synonyms: Alpha hemolysin; Alpha HL; Alpha toxin; Hla; Hly; Staphylococcus alpha HL; Staphylococcus alpha toxin
• UniProt ID: P09616

Gene Information

• Official Symbol: HLY
• Synonyms: Alpha hemolysin; Alpha HL; Alpha toxin; Hla; Hly; Staphylococcus alpha HL; Staphylococcus alpha toxin
• UniProt ID: P09616

Reviews

03/21/2018

Whether it's modifying protocols, providing custom formulations, or offering personalized recommendations, their flexibility ensures that I have the necessary tools to carry out my experiments seamlessly.

01/17/2018

The combination of exceptional quality, reliable performance, and dedicated customer service makes them an invaluable partner in my research journey.

12/02/2016

Their proactive approach ensures that I am always working with the latest advancements in HLY protein research, allowing me to explore new avenues and potentially uncover groundbreaking discoveries.

Q&As

What other medical conditions can benefit from HLY protein-based drug delivery?

HLY protein can be used in various diseases, including infectious diseases, genetic disorders, and neurological conditions.

Can HLY protein be used in cancer treatment?

Yes, it can be used to deliver chemotherapy drugs directly to cancer cells.

Can HLY protein be used for diagnostics?

Yes, it can be used in diagnostic assays to detect specific cells or molecules in clinical samples.

How does HLY protein assist in drug delivery?

HLY protein can be engineered to create pores in the membranes of specific cells, allowing drugs to enter these cells more effectively.

How can HLY protein be used in clinical applications?

HLY protein has several clinical applications due to its ability to create pores in cell membranes.