Recombiant Hmuan Ubiquitin Related Modifier 1, His-tagged

• Cat.No.: URM1-63H
• Product Overview: Recombinant human URM1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Cat. No.: URM1-63H
• Description: URM1 is ubiquitin-related modifier 1 homolog protein that primarily functions in the post-translational modification of proteins by way of the urmylation pathway. In studies with Saccharomyces cerevisiae, it has been found that Urm1 covalently binds to its E1 activating enzyme, Uba4p, to conjugate alkyl hydroperoxidereductase (Ahp1). It is hypothesized that this complex may then play a role in the oxidative-stress response in mammals.
• Formulation: Liquid. In 20mM Tris-HClbuffer(pH 8.0) containing 10% glycerol, 1mM DTT.
• Molecular Weight: 13.5 kDa (121 aa) confirmed by MALDI-TOF
• Purity: > 95% by SDS – PAGE
• Concentration: 1 mg/ml (determined by Bradford assay)
• Sequences of animo acids: MGSSHHHHHH SSGLVPRGSHMAAPLSVEVE FGGGAELLFD GIKKHRVTLP GQEEPWDIRN LLIWIKKNLL KERPELFIQG DSVRPGILVL INDADWELLG ELDYQLQDQD SVLFISTLHG G
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: URM1 ubiquitin related modifier 1 [ Homo sapiens ]
• Synonyms: URM1;ubiquitin related modifier 1;C9orf74; MGC2668; RP11-339B21.4;ubiquitin related modifier 1 homolog;chromosome 9 open reading frame 74;ubiquitin related modifier 1 homolog
• Gene ID: 81605
• MIM: 612693
• mRNA Refseq: NM_030914
• Protein Refseq: NP_112176
• UniProt ID: Q9BTM9
• Chromosome Location: 9q34.13
• Function: protein binding; contributes_tosulfurtransferase activity