URM1
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Official Full Name
ubiquitin related modifier 1 -
Overview
Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is t -
Synonyms
URM1;ubiquitin related modifier 1;C9orf74, chromosome 9 open reading frame 74 , ubiquitin related modifier 1 homolog (S. cerevisiae);ubiquitin-related modifier 1 homolog;MGC2668;ubiquitin related modifier 1 homolog;C9orf74;RP11-339B21.4
Recombinant Proteins
- Chicken
- Mouse
- Human
- Rhesus macaque
- Mammalian Cells
- E.coli
- HEK293
- His
- Non
- DDK
- Myc
- GST
- Avi
- Fc
Involved Pathway
URM1 involved in several pathways and played different roles in them. We selected most pathways URM1 participated on our site, such as Sulfur relay system, which may be useful for your reference. Also, other proteins which involved in the same pathway with URM1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Sulfur relay system | MOCS2,CTU1,TRMU,MPST,NFS1,LBH,MOCS3,MOCS1,CTU2,TST |
Protein Function
URM1 has several biochemical functions, for example, protein binding,contributes_to sulfurtransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by URM1 itself. We selected most functions URM1 had, and list some proteins which have the same functions with URM1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| contributes_to sulfurtransferase activity | LBH |
| protein binding | HSPA13,RIPPLY1,RBMY1A1,RUFY3,YBX1,PAK6,FGD5,SET,PPIL3,NUP133 |
Interacting Protein
URM1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with URM1 here. Most of them are supplied by our site. Hope this information will be useful for your research of URM1.
CDK11B;VIPR2;TBL3;fliN;ASCC2
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References
- Collaud, S; Tischler, V; et al. Lung neuroendocrine tumors: correlation of ubiquitinylation and sumoylation with nucleo-cytosolic partitioning of PTEN. BMC CANCER 15:-(2015).
- Yuan, YF; Zhai, R; et al. SUMO-1 Plays Crucial Roles for Spindle Organization, Chromosome Congression, and Chromosome Segregation During Mouse Oocyte Meiotic Maturation. MOLECULAR REPRODUCTION AND DEVELOPMENT 81:712-724(2014).
