Rabbit Anti-Human DUOX2 Polyclonal Antibody

• Cat.No.: CPBT-32950RH

Specification

• Species: Human
• Source: Rabbit
• Tag: Non
• ProductOverview: Rabbit polyclonal to human DUOX2.
• Antigen Description: The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX1. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain.
• Immunogen: Synthetic peptide corresponding to internal sequence amino acids of Human DUOX2.
• Host animal: Rabbit
• Cross reactivity: Reacts with Rat, Human; Predicted to work withMouse
• Isotype: IgG
• Purity: Immunogen affinity purified
• Applications: WB, IHC-P
• Positive control: HeLa, Jurkat, MCF7 and SMMC cell lysates.
• Sequencesimilarities: In the N-terminal section; belongs to the peroxidase family.Contains 3 EF-hand domains.Contains 1 FAD-binding FR-type domain.Contains 1 ferric oxidoreductase domain.
• Concentration: 100 µg at 0.5mg/ml
• Form: Liquid
• Storage Buffer: Preservatives: 0.025% Thimerosal (merthiolate), 0.025% Sodium azideConstituents: 0.1% Dibasic monohydrogen sodium phosphate, 0.45% Sodium chloride, 2.5% BSA
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
• Function: NAD(P)H oxidase activity; calcium ion binding; heme binding; peroxidase activity

Gene Information

• Gene Name: DUOX2 dual oxidase 2 [ Homo sapiens ]
• Official Symbol: DUOX2
• Synonyms: DUOX2; dual oxidase 2; TDH6; LNOX2; THOX2; NOXEF2; P138-TOX; dual oxidase 2; long NOX 2; large NOX 2; thyroid oxidase 2; p138 thyroid oxidase; NADPH thyroid oxidase 2; flavoprotein NADPH oxidase; dual oxidase-like domains 2; NADPH oxidase/peroxidase DUOX2; NADH/NADPH thyroid oxidase p138-tox; nicotinamide adenine dinucleotide phosphate oxidase; EC 1.6.3.1; EC 1.11.1
• Gene ID: 50506
• mRNA Refseq: NM_014080
• Protein Refseq: NP_054799
• MIM: 606759
• UniProt ID: Q9NRD8
• Chromosome Location: 15q15.3
• Pathway: NOD pathway, organism-specific biosystem