Native Rat Alpha-2-Macroglobulin

• Cat.No.: A2m-695R
• Product Overview: Native Rat A2m isprepared from Rat serum.

Specification

• Species: Rat
• Source: Rat serum
• Tag: Non
• Description: Nativerat A2m is a large plasma protein found in the blood. A2m is produced by theliver and is a major component of the alpha-2 band in proteinelectrophoresis.
• Form: Lyophilized from 10 mM sodium phosphate buffer, pH 7.2, +10 mM NaCl.
• Purity: > 90% asdetermined by SDS-PAGE analysis
• Concentration: Reconstitute with water at 0.5 mg/ml
• Molecular Weight: 175 kDa
• Endotoxin Level: 1eu/ug of protein
• Storage: Store at -80°C.Stable for 1 year. Avoid repeated freeze-thaw cycles.
• Pathways: Complement and Coagulation Cascades;Formation of Fibrin Clot (Clotting Cascade); Hemostasis; Intrinsic Pathway;Platelet activation; Platelet degranulation; Rho GTPase cycle; SignalTransduction; Signaling by Rho GTPases

Gene Information

• Gene Name: A2malpha-2-macroglobulin [ Rattus norvegicus ]
• Official Symbol: A2m
• Synonyms: A2m;alpha-2-macroglobulin; Mam; A2m1; A2maa; A2MAC1; MGC114358;RATA2MAC1; alpha-2-macroglobulin; alpha-2-M; alpha-2-macroglobulin-P
• Gene ID: 24153
• mRNA Refseq: NM_012488
• Protein Refseq: NP_036620
• MIM: P06238
• Chromosome Location: 4
• Function: endopeptidaseinhibitor activity; enzyme binding; growth factor binding; interleukin-1binding; interleukin-8 binding; peptidase inhibitor activity; receptorbinding; serine-type endopeptidase inhibitor activity; tumor necrosis factorbinding