Native Human TIMP1
Cat.No. : | TIMP1-30840TH |
Product Overview : | TIMP1 is purified from stimulated human fibroblasts, and is essentially free of contaminating MMPs or other known TIMPs. |
- Specification
- Gene Information
- Related Products
- Download
Species : | Human |
Source : | Human Fibroblasts |
Tag : | Non |
Description : | This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. |
Form : | Liquid |
Purity : | >95 % by SDS-PAGE. |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.Preservative: NoneConstituents: 50% Glycerol, PBS, pH 7.4 |
Concentration : | 0.1 mg/ml |
Gene Name | TIMP1 TIMP metallopeptidase inhibitor 1 [ Homo sapiens (human) ] |
Official Symbol | TIMP1 |
Synonyms | TIMP1; TIMP metallopeptidase inhibitor 1; EPA; EPO; HCI; CLGI; TIMP; FLJ90373; tissue inhibitor of metalloproteinase 1; erythroid potentiating activity; fibroblast collagenase inhibitor; tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor); Tissue inhibitor of metalloproteinases; TIMP-1; Collagenase inhibitor; OTTHUMP00000023214; Erythroid-potentiating activity |
Gene ID | 7076 |
mRNA Refseq | NM_003254 |
Protein Refseq | NP_003245 |
MIM | 305370 |
UniProt ID | P01033 |
Chromosome Location | Xp11.3-p11.23 |
Pathway | Activation of Matrix Metalloproteinases; Matrix Metalloproteinases; Platelet degranulation |
Function | cytokine activity; protease binding; metal ion binding |
◆ Recombinant Proteins | ||
RFL15866PF | Recombinant Full Length Pan Troglodytes 5-Hydroxytryptamine Receptor 1F(Htr1F) Protein, His-Tagged | +Inquiry |
FOXP3-51H | Recombinant Human Forkhead box P3, GST-tagged | +Inquiry |
CFAP36-3756Z | Recombinant Zebrafish CFAP36 | +Inquiry |
RFL10365DF | Recombinant Full Length Drosophila Melanogaster Putative Odorant Receptor 98A(Or98A) Protein, His-Tagged | +Inquiry |
MRPL50-5594H | Recombinant Human MRPL50 Protein, GST-tagged | +Inquiry |
◆ Native Proteins | ||
Proteasome 20S-37H | Native Human Proteasome 20S Protein, Tag Free | +Inquiry |
Lipoproteins-13H | Natve Human Lipoproteins, Very Low Density | +Inquiry |
CNTF-26839TH | Native Human CNTF | +Inquiry |
Fixa-279B | Active Native Bovine Factor IXa - EGR | +Inquiry |
Pancreas-002H | Human Pancreas Lysate, Total Protein | +Inquiry |
◆ Cell & Tissue Lysates | ||
PPP2R5C-2917HCL | Recombinant Human PPP2R5C 293 Cell Lysate | +Inquiry |
KIR3DS1-365HCL | Recombinant Human KIR3DS1 lysate | +Inquiry |
DCX-7032HCL | Recombinant Human DCX 293 Cell Lysate | +Inquiry |
RPL5-2192HCL | Recombinant Human RPL5 293 Cell Lysate | +Inquiry |
CD207-7680HCL | Recombinant Human CD207 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
Inquiry
- Reviews
- Q&As
Ask a Question for All TIMP1 Products
Required fields are marked with *
My Review for All TIMP1 Products
Required fields are marked with *
0
Inquiry Basket