Native Human Lipoprotein

Description :	In a normal fasting individual, low density lipoprotein concentrations range from 2.0 - 3.5 g/L. LDL constitutes 50% of the total lipoprotein mass in plasma and is the major carrier of cholesterol and cholesteryl esters. LDL levels strongly correlate with coronary heart disease.
Source :	Human plasma
Species :	Human
Form :	Liquid
Molecular Mass :	2,300.0 kDa
Purity :	Purity by SDS-PAGE: ≥95%; Purity by HPLC: ≥95%
Usage :	For Research Use Only! Not For Use in Humans.
Notes :	Centrifuge the vial prior to opening
Storage :	4°C
Storage Buffer :	250 μl liquid in 150 mM NaCl, pH 7.4, and 0.01% EDTA
Shipping :	Gel pack
Tag :	Non

Gene Name	LDLR low density lipoprotein receptor [ Homo sapiens ]
Official Symbol	LDLR
Synonyms	LDLR; low density lipoprotein receptor; low-density lipoprotein receptor; familial hypercholesterolemia; LDL receptor; low-density lipoprotein receptor class A domain-containing protein 3; FH; FHC; LDLCQ2;
Gene ID	3949
mRNA Refseq	NM_000527
Protein Refseq	NP_000518
MIM	606945
UniProt ID	P01130
Chromosome Location	19p13.2
Pathway	Bile secretion, organism-specific biosystem; Bile secretion, conserved biosystem; Chylomicron-mediated lipid transport, organism-specific biosystem; DNA damage response (only ATM dependent), organism-specific biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; Hepatitis C, organism-specific biosystem;
Function	calcium ion binding; glycoprotein binding; low-density lipoprotein receptor activity; protein binding; receptor activity; very-low-density lipoprotein particle receptor activity;