Native Human Gamma-Glutamyltransferase 1

• Cat.No.: GGT1-5353H
• Product Overview: Native Human GGT1 isprepared from Human Liver.

Specification

• Species: Human
• Source: Human Liver
• Tag: Non
• Description: Theenzyme catalyzes the transfer of the GGT1 to a variety of amino acids anddipeptide acceptors. The enzyme is composed of a heavy chain and a lightchain, which are derived from a single precursor protein, and is present intissues involved in absorption and secretion. The GGT1 is useful in thedetection of liver disease, obstructive jaundice, cholangitis, infectioushepatitus, and cholecystitis. It can also be used to detect diseases of thekidney and to differentiate liver or bile duct (hepatobiliary) disorders frombone disease.
• Form: Ammonia SulfateSuspension
• Concentration: > 2 mg/ml
• Biological Activity: One unit willcatalyze the transfer of one micromole of the glutamyl moiety fromgamma-glutamyl-p-nitroanilide hydrochloride (gamma-GPNA-HCl) to glycylglycineat 37oC.Measured at 405 nm as directly proportional formation of p-nitroaniline.
• Endotoxin Level: < 0.1 ng/ug ofprotein
• Specific Activity: > 50 U/mg proteinat 37oC
• Storage: Store at -2-4oC. Stablefor 1 year.
• Pathways: Arachidonic acid metabolism;Cyanoamino acid metabolism; Eicosanoid Synthesis; Glutathione metabolism;Metabolic pathways; Selenium Pathway; Taurine and hypotaurine metabolism;gamma-glutamyl cycle

Gene Information

• Gene Name: GGT1gamma-glutamyltransferase 1 [ Homo sapiens ]
• Official Symbol: GGT1
• Synonyms: GGT1; gamma-glutamyltransferase1; GGT; GTG; CD224;D22S672; D22S732; MGC96892; MGC96904; MGC96963; GGT1;gamma-glutamyltranspeptidase1; glutamyl transpeptidase;gamma-glutamyltranspeptidase; CD224 antigen gamma-glutamyltransferase 1
• Gene ID: 2678
• mRNA Refseq: NM_001032364
• Protein Refseq: NP_001027536
• MIM: 612346
• UniProt ID: P19440
• Chromosome Location: 22q11
• Function: acyltransferase activity;gamma-glutamyltransferase activity; protein binding; transferase activity