Native Human Ferritin, Heavy Polypeptide 1

• Cat.No.: FTH1-1868H
• Product Overview: Native Human FTH1 isprepared from Human Placenta.

Specification

• Species: Human
• Source: Human Placenta
• Tag: Non
• Description: FTH1is a 450 kDa globular protein complex consisting of 24 subunits that ispresent in every cell type and is the primary intracellular iron-storageprotein. FTH1 is responsible for keeping iron in a soluble and non-toxicform. In vertebrates, these subunits are both the light (L) and the heavy (H)type with an apparent molecular weight of 19 kDa or 21 kDa respectively.
• Form: 50 mM Tris-HClBuffer, pH 7.5+0.15 M NaCl
• Molecular Weight: 450 kDa
• Purity: > 96% byelectrophoresis
• Concentration: Typically >1.0mg/mL
• Storage: Store at 2-4oC. Do notfreeze. 1 year.
• Pathways: Clathrin derived vesicle budding; GolgiAssociated Vesicle Biogenesis; Membrane Trafficking; Mineral absorption; Porphyrinand chlorophyll metabolism; Validated targets of C-MYC transcriptionalrepression; trans-Golgi Network Vesicle Budding

Gene Information

• Gene Name: FTH1ferritin, heavy polypeptide 1 [ Homo sapiens ]
• Official Symbol: FTH1
• Synonyms: FTH1; ferritin,heavy polypeptide 1; FHC; FTH; PLIF; FTHL6; PIG15; MGC104426; FTH1;apoferritin; placenta immunoregulatory factor; proliferation-inducing protein15; EC 1.16.3.1; apoferritin; Ferritin H subunit
• Gene ID: 2495
• mRNA Refseq: NM_002032
• Protein Refseq: NP_002023
• MIM: 134770
• UniProt ID: P02794
• Chromosome Location: 11q13
• Function: ferric iron binding; ferric iron binding; ferroxidase activity; oxidoreductaseactivity; protein binding