Recombinant Human FTH1 protein, His & T7-tagged

• Cat.No.: FTH1-8237H
• Product Overview: Recombinant Human FTH1 aa. (Met1~Ser183 (Accession # P02794)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Description: This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined.
• Source: E. coli
• Species: Human
• Tag: His&T7
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 25.0kDa.
• Protein length: Met1~Ser183
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 5.9.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage Buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: FTH1 ferritin heavy chain 1 [ Homo sapiens (human) ]
• Official Symbol: FTH1
• Synonyms: FTH1; ferritin heavy chain 1; FHC; FTH; HFE5; PLIF; FTHL6; PIG15; ferritin heavy chain; apoferritin; cell proliferation-inducing gene 15 protein; ferritin H subunit; ferritin, heavy polypeptide 1; placenta immunoregulatory factor; proliferation-inducing protein 15
• Gene ID: 2495
• mRNA Refseq: NM_002032.2
• Protein Refseq: NP_002023.2
• UniProt ID: P02794