Native Human Apolipoprotein H (beta-2-glycoprotein I)

• Cat.No.: APOH-5365H
• Product Overview: Native human APOH was expressed in Human plasma.

Specification

• Species: Human
• Source: Human Plasma
• Tag: Non
• Description: APOH, also known asbeta2Glycoprotein-1 (B2GP-1) is a plasma glycoprotein that circulates at aconcentration of 200 ug/mL (4mM). B2GP-1 has been identified as a constituentof chylomicrons, very low density lipoproteins and high density lipoproteinsin Human plasma. It has also been demonstrated to bind phospholipids, heparinand platelets where it can modulate the activity of adenylate (19percent).Although the precise functions) are as yet unknown, B2GP-1 has been shown tointerfere with blood coagulation by competitively binding to phospholipidsexposed during cell activation or damage.
• Form: Liquid in 0.02MTris-HCI+0.3M NaCI, pH 7.3.
• Molecular Mass: 48000
• Purity: ≥95% by SDS-PAGEanalysis
• Storage: When stored at -80°C product is stable for 3 years from date of delivery. Avoid repeated freeze-thawcycles.
• Concentration: 1.0 mg/ml

Gene Information

• Gene Name: APOH apolipoprotein H (beta-2-glycoprotein I) [ Homo sapiens ]
• Official Symbol: APOH
• Synonyms: APOH; apolipoprotein H (beta-2-glycoprotein I); B2G1; beta-2-glycoprotein 1; beta 2 glycoprotein I; BG; B2GPI; apo-H; beta(2)GPI; APC inhibitor; anticardiolipin cofactor; activated protein C-binding protein; B2GP1
• Gene ID: 350
• mRNA Refseq: NM_000042
• Protein Refseq: NP_000033
• MIM: 138700
• UniProt ID: P02749
• Chromosome Location: 17q23-qter
• Function: eukaryotic cell surface binding; glycoprotein binding; heparin binding; lipid binding; lipoprotein lipase activator activity; phospholipid binding; protein binding