APOH
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Official Full Name
apolipoprotein H (beta-2-glycoprotein I) -
Overview
Apolipoprotein H has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome, but it does not seem to be required for the reactivity of antiphospholipid autoantibodies associated with infections. -
Synonyms
APOH;apolipoprotein H (beta-2-glycoprotein I);B2G1;beta-2-glycoprotein 1;beta 2 glycoprotein I;BG;Activated protein C binding protein;Activated protein C-binding protein;Anticardiolipin cofactor;APC inhibitor;Apo-H;APOH;APOH_HUMAN;Apolipoprotein H;B2G1;B2GPI;beta 2 glycoprotein I;beta 2 glycoprotein I precursor;BetaGPI;Beta-2-glycoprotein 1;Beta-2-glycoprotein I;BG;OTTMUSP00000003033;B2GPI;apo-H;betaGPI;APC inhibitor;anticardiolipin cofactor;activated protein C-binding protein;B2GP1
Recombinant Proteins
- Human
- Cynomolgus
- Rat
- Mouse
- Cattle
- Dog
- Chicken
- E.coli
- HEK293
- C-His
- Mammalian Cell
- Wheat Germ
- Sf9 Insect Cell
- Human Cell
- Mammalian cells
- In Vitro Cell Free System
- HEK293T
- Human Plasma
- Insect Cell
- Human plasma
- GST
- His
- FITC
- Non
- Myc&DDK
- His&Fc&Avi
- N-His-GST
Involved Pathway
APOH involved in several pathways and played different roles in them. We selected most pathways APOH participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with APOH were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
APOH has several biochemical functions, for example, glycoprotein binding,heparin binding,identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by APOH itself. We selected most functions APOH had, and list some proteins which have the same functions with APOH. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | MT2A,PRKCB,RPLP1,BNIP1,PCSK2,TRPC4AP,VDAC1,TBX5,FTCD,NCS1 |
| heparin binding | MMP7,NRP2,PLA2G2D,HSD17B12,SFRP1,APOB,THBS4,PDCD5,SOST,FMODA |
| glycoprotein binding | PIP,SHB,RASA1,VWF,TGFB1,SERPINA1E,TFRC,CNTN1,BMPR1A,VIM |
| phospholipid binding | NBEAA,NSFL1C,SPTBN2,ANXA1,NBEAL2,LPAR3,HIP1RB,PLA2G15,NBEA,SYTL4 |
| lipoprotein lipase activator activity | APOC2,APOA5 |
| identical protein binding | APOA1,ADIPOR1,SUN2,IGF2R,CLDN11,AMOTL2,RAD52,EDC3,FZD1,ITGA2B |
| lipid binding | BPIFA5,FAM125A,PCYT1A,FABP7A,Ar,YBX2,STARD10,S100A13,DOK7,CADPS |
Interacting Protein
APOH has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with APOH here. Most of them are supplied by our site. Hope this information will be useful for your research of APOH.
LPA;PLG;TP53;AKT1;GEM;CDC42;GRB2;CLEC4G;RBBP6;q99ib8-pro_0000045596
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References
- Kolyada, A; Karageorgos, I; et al. An A1-A1 mutant with improved binding and inhibition of beta 2GPI/antibody complexes in antiphospholipid syndrome. FEBS JOURNAL 282:864-873(2015).
- Thammasri, K; Rauhamaki, S; et al. Human Parvovirus B19 Induced Apoptotic Bodies Contain Altered Self-Antigens that are Phagocytosed by Antigen Presenting Cells. PLOS ONE 8:-(2013).
