Native Human APCS

• Cat.No.: APCS-31189TH
• Product Overview: Full length native Human Serum Amyloid P purified from normal Human serum/plasma, MWt 250kDa.

Specification

• Description: The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.
• Protein length: 204 amino acids
• Molecular Weight: 250.000kDa
• Form: Liquid
• Storage buffer: Preservative: 0.09% Sodium AzideConstituents: 0.14M Sodium chloride, 0.01M EDTA, 0.01M Tris, pH 8.0
• Storage: Store at +4°C.
• Tag: Non

Gene Information

• Gene Name: APCS amyloid P component, serum [ Homo sapiens ]
• Official Symbol: APCS
• Synonyms: APCS; amyloid P component, serum; serum amyloid P-component; 9.5S alpha 1 glycoprotein; MGC88159; pentaxin related; PTX2; SAP
• Gene ID: 325
• mRNA Refseq: NM_001639
• Protein Refseq: NP_001630
• MIM: 104770
• Uniprot ID: P02743
• Chromosome Location: 1q21-q23
• Pathway: Amyloids, organism-specific biosystem
• Function: metal ion binding; sugar binding; unfolded protein binding