Native Human Amylase, Alpha 2B (pancreatic)

• Cat.No.: AMY2B-1858H
• Product Overview: Native human AMY2B wasexpressed in Human Pancreas.

Specification

• Species: Human
• Source: Human Pancreas
• Tag: Non
• Description: Amylases aresecreted proteins that hydrolyze 1,4-alpha-glucoside bonds inoligosaccharides and polysaccharides, and thus catalyze the first step indigestion of dietary starch and glycogen. The human genome has a cluster ofseveral amylase genes that are expressed at high levels in either salivarygland or pancreas. This gene encodes an amylase isoenzyme produced by thepancreas.
• Form: Aqueous buffer of100 mM Tris-HCL+150 mM NaCl.
• Biological Activity: Typically > 400Units/ml at 37 oC. One unit will catalyze thehydrolysis of one of malto pentaose, which through coupled reactions resultsin the formation of 5 of glucose-6-phosphate per minute at 37 oC.Measured at 340 nm as an equimolar amount of NADH produced by a coupledreaction.
• Purity: > 95.0% asdetermined by RP-HPLC and SDS-PAGE analyses.
• Storage: Liquid is stable for1 year at 2-4oC. Avoid repeated freeze-thaw cycles.
• Pathways: Carbohydrate digestion and absorption; Digestionof dietary carbohydrate; Metabolic pathways; Metabolism of carbohydrates; Pancreaticsecretion; Starch and sucrose metabolism

Gene Information

• Gene Name: AMY2B amylase, alpha 2B(pancreatic) [ Homo sapiens ]
• Official Symbol: AMY2B
• Synonyms: AMY2B; amylase,alpha 2B (pancreatic); AMY2; alpha-amylase 2B;glycogenase; OTTHUMP00000012696; OTTHUMP00000012697; alpha-amylase carcinoid;carcinoid alpha-amylase; 1,4-alpha-D-glucan glucanohydrolase 2B; EC 3.2.1.1
• Gene ID: 280
• mRNA Refseq: NM_020978
• Protein Refseq: NP_066188
• MIM: 104660
• UniProt ID: P19961
• Chromosome Location: 1
• Function: alpha-amylaseactivity; hydrolase activity, acting on glycosyl bonds; metal ion binding