Native Human AMY2A

• Cat.No.: AMY2A-8353H
• Product Overview: Native Human AMY2A was purified from Pancrease.

Specification

• Species: Human
• Source: Pancreas
• Tag: Non
• Description: Alpha amylase is a polysaccharide-hydrolyzing enzyme secreted in the pancreas and salivary glands. Increased serum levels are seen in acute pancreatitis: the amount of amylase in the blood rises within 3 to 6 hours of onset, peaking at up to 40 times the normal level (after 20 to 30 hours) with normal levels re-established within 2 to 8 days. High blood amylase levels may also be due to impaired glomerular filtration leading to reduced renal elimination.
• Form: Liquid in 0.1M TRIS buffer, pH 7.5, containing 0.15M NaCl, 1mM calcium chloride, 1mM benzamidine and 1mM pefabloc.
• Unit Definition: One unit will catalyse the hydrolysis of one micromole of malto-pentaose, which through coupled reactions results in the formation of 5 micromoles of glucose-6- phosphate per minute at 37°C. Measured at 340nm as an equimolar amount of NADH produced by a coupled reaction.

Gene Information

• Gene Name: AMY2A amylase, alpha 2A (pancreatic) [ Homo sapiens ]
• Official Symbol: AMY2A
• Synonyms: AMY2A; amylase, alpha 2A (pancreatic); AMY2, amylase, alpha 2A; pancreatic; pancreatic alpha-amylase; glycogenase; alpha-amylase; found in the pancreas; pancreatic amylase 2A; pancreatic amylase alpha 2A; amylase, pancreatic, alpha-2A; 1,4-alpha-D-glucan
• Gene ID: 279
• mRNA Refseq: NM_000699
• Protein Refseq: NP_000690
• MIM: 104650
• UniProt ID: P04746
• Chromosome Location: 1p21.1
• Pathway: Carbohydrate digestion and absorption, organism-specific biosystem; Carbohydrate digestion and absorption, conserved biosystem; Digestion of dietary carbohydrate, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of carbohydrates, organism-specific biosystem; Pancreatic secretion, organism-specific biosystem
• Function: alpha-amylase activity; calcium ion binding; chloride ion binding; hydrolase activity, acting on glycosyl bonds