Mouse Anti-IL4 Monoclonal Antibody

• Cat.No.: DMABT-H19228
• Product Overview: Mouse Anti-IL4 Monoclonal Antibody

Specification

• Species: Human
• Source: Mouse
• Tag: Alexa Fluor
• Antigen Description: IL-4 is a pleiotropic cytokine that is produced by activated T cells mast cells and basophils.JM-5elicits many different biological responses, but has two dominant functions. The first is regulating differentiation of na?ve CD4+T cell to the Th2 type. Th2 cells produce IL-4, IL-5, IL-10 and IL-13, which tend to favor a humoral immune response while suppressing a cell-mediated immune response controlled by Th1 cells. The second is regulating IgE and IgG1 production by B cells. The9E5-9antibody can neutralize the bioactivity of natural or recombinant IL-4.
• Target: IL4
• Immunogen: Yeast-expressed, recombinant human IL-4
• Isotype: IgG1, kappa
• species: Human
• Clone: 9E5-9
• Conjugation: Alexa Fluor 488
• Applications: N/A
• Preparation: The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor 488 under optimal conditions. The solution is free of unconjugated Alexa Fluor 488.
• Usage recommendation: Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 5 μl per million cells or 5 μl per 100 μl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.* Alexa Fluor 488 has a maximum emission of 519 nm when it is excited at 488 nm.** Alexa Fluor 488 is a registered trademark of Molecular Probes, Inc. Alexa Fluor 488 dye antibody conjugates are sold under license from Molecular Probes, Inc. for research use only, except for use in combination with microarrays and high content screening, and are covered by pending and issued patents.View full statement regarding label licenses
• Storage: The antibody solution should be stored undiluted at 4 °C and protected from prolonged exposure to light.Do not freeze.
• Size: 25 tests;100 tests

Gene Information

• Gene Name: IL4 interleukin 4 [ Homo sapiens ]
• Official Symbol: IL4
• Synonyms: IL4; interleukin 4; interleukin-4; B cell growth factor 1; B_cell stimulatory factor 1; BCGF 1; BCGF1; BSF1; IL 4; lymphocyte stimulatory factor 1; MGC79402; binetrakin; pitrakinra; IL-4; BSF-1; BCGF-1
• Gene ID: 3565
• mRNA Refseq: NM_000589
• Protein Refseq: NP_000580
• MIM: 147780
• UniProt ID: P05112
• Chromosome Location: 5q23-q31
• Pathway: Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Asthma, organism-specific biosystem; Asthma, conserved biosystem; Autoimmune thyroid disease, organism-specific biosystem; Autoimmune thyroid disease, conserved biosystem; CD40/CD40L signaling, organism-specific biosystem
• Function: cytokine activity; growth factor activity; interleukin-4 receptor binding; protein binding