Recombinant Human CAMK2B, His-tagged, Active

• Cat.No.: CAMK2B-265H
• Product Overview: Recombinant full-length human CAMK2beta was expressed by baculovirus inSf9cells using an N-terminal His tag. MW = 58 kDa.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: His
• Description: CAMK2β belongs to the serine/threonine protein kinase family and to the type II multifunctional Ca(2+)/calmodulin-dependent protein kinase subfamily. CAMK2β showed wide tissue and cell distribution, and one of CAMK2β variant predominated in adult brain. The ratio of CAMK2α and CAMK2β protein levels were inversely related during activity in hippocampal neurons. CAMK2β is a prominent kinase in the central nervous system and may function in long-term potentiation and neurotransmitter release.
• Sequence: Full-length.
• Applications: Kinase Assay, Western Blot.
• Storage And Stability: Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Gene Information

• Gene Name: CAMK2B calcium/calmodulin-dependent protein kinase II beta [ Homo sapiens ]
• Synonyms: CAMK2B; calcium/calmodulin-dependent protein kinase II beta; CAM2; CAMK2; CAMKB; MGC29528; OTTHUMP00000159355; OTTHUMP00000159356; OTTHUMP00000209343; CaM-kinase II beta chain; CaM kinase II beta subunit; proline rich calmodulin-dependent protein kinase; calcium/calmodulin-dependent protein kinase type II beta chain; EC 2.7.11.17; CaM kinase II subunit beta; CaMK-II subunit beta
• Gene ID: 816
• mRNA Refseq: NM_001220
• Protein Refseq: NP_001211
• MIM: 607707
• UniProt ID: Q13554
• Chromosome Location: 22q12; 7p14.3-p14.1
• Pathway: Calcium signaling pathway; ErbB signaling pathway; Glioma; GnRH signaling pathway; Long-term potentiation; Melanogenesis; Neurotrophin signaling pathway; Olfactory transduction; Wnt signaling pathway
• Function: ATP binding; calmodulin binding; calmodulin-dependent protein kinase activity; nucleotide binding; transferase activity