Active Recombinant Rat Havcr1 Protein, His-tagged

• Cat.No.: Havcr1-986R
• Product Overview: Recombinant Rat Havcr1 (Accession # O54947) Ser18-Val238, fused with a C-terminal 6-His tag, was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Species: Rat
• Source: Mammalian Cells
• Tag: His
• Protein Length: Ser18-Val238
• Predicted N Terminal: Ser18
• Form: Lyophilized from a 0.2 µm filtered solution in PBS.
• Bio-activity: Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated human T cells.Human T lymphocytes cultured for 72 hours with PHA were incubated for an additional 3 days in 96 well plates coated with 500 ng/mL anti-CD3 and rrKIM-1.The ED50 for this effect is typically 0.4-2 µg/mL.Optimal dilutions should be determined by each laboratory for each application.
• Molecular Mass: Recombinant Rat Havcr1, His-tagged has a calculated MW of 25.4 kDa. In SDS-PAGE migrates as 55-65 kDa, reducing conditions.
• Purity: >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: Havcr1 hepatitis A virus cellular receptor 1 [ Rattus norvegicus ]
• Official Symbol: Havcr1
• Synonyms: HAVCR1; hepatitis A virus cellular receptor 1; hepatitis A virus cellular receptor 1 homolog; TIMD-1; HAVcr-1; kidney injury molecule 1; t cell immunoglobulin and mucin domain-containing protein 1; Kim1; KIM-1
• Gene ID: 286934
• mRNA Refseq: NM_173149
• Protein Refseq: NP_775172