Active Recombinant Mouse Wnt3a protein

Source :	Cell Culture
Species :	Mouse
Bio-activity :	The ED50 was determined by its ability to induced alkaline phosphatase production by CCL-226 cells. The expected ED50 for this effect is 0.4-0.6 ng/ml.
Molecular Mass :	Due to glycosylation, the murine Wnt-3a migrates at an apparent molecular weight of approximately 38.0-41.0 kDa by SDS-PAGE analysis under non-reducing conditions.
AA Sequence :	SYPIWWSLA VGPQYSSLS TQPILCASI PGLVPKQLR FCRNYVEIM PSVAEGVKA GIQECQHQF RGRRWNCTT VSNSLAIFG PVLDKATRE SAFVHAIAS AGVAFAVTR SCAEGSAAI CGCSSRLQG SPGEGWKWG GCSEDIEFG GMVSREFAD ARENRPDAR SAMNRHNNE AGRQAIASH MHLKCKCHG LSGSCEVKT CWWSQPDFR TIGDFLKDK YDSASEMVV EKHRESRGW VETLRPRYT YFKVPTERD LVYYEASPN FCEPNPETG SFGTRDRTC NVSSHGIDG CDLLCCGRG HNARTERRR EKCHCVFHW CCYVSCQEC TRVYDVHTC K
Purity :	Above 75% as determined by SDS-PAGE Analysis.
Tag :	Non

Gene Name	Wnt3a wingless-related MMTV integration site 3A [ Mus musculus ]
Official Symbol	Wnt3a
Synonyms	WNT3A; wingless-related MMTV integration site 3A; protein Wnt-3a; vestigial tail; vt; Wnt-3a;
Gene ID	22416
mRNA Refseq	NM_009522
Protein Refseq	NP_033548
MIM
UniProt ID	P27467
Chromosome Location	11 B1.3; 11 37.17 cM
Pathway	Basal cell carcinoma, organism-specific biosystem; Basal cell carcinoma, conserved biosystem; Class B/2 (Secretin family receptors), organism-specific biosystem; ESC Pluripotency Pathways, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem;
Function	frizzled binding; frizzled-2 binding; protein binding; protein domain specific binding; receptor agonist activity; receptor binding; transcription coactivator activity;