Active Recombinant Mouse Thpo Protein

• Cat.No.: Thpo-6417M
• Product Overview: Purified recombinant protein of Mouse thrombopoietin (Thpo), transcript variant 2 without tag was expressed in CHO.

Specification

• Species: Mouse
• Source: CHO
• Protein Length: Ser22-Thr356
• Description: This gene encodes a humoral growth factor necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. The encoded protein is a ligand for the product of the myeloproliferative leukemia virus oncogene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
• Bio-activity: The ED50 is less than 0.8 ng/mL.
• Molecular Mass: 35.5 kDa
• Endotoxin: Less than 1.0 EU/μg protein as determined by the LAL method
• Purity: > 90%, as determined by Coomassie stained SDS-PAGE.
• Stability: Unopened vial can be stored between 2 and 8 centigrade for up to 2 weeks, at -20 centigrade for up to 6 months, or at -70 centigrade or below until the expiration date. Aliquots can be stored between 2 and 8 centigrade for up to one week and stored at -20 centigrade or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: Protein formulated and vialed at >50 μg/mL in specified buffer
• Storage Buffer: 1 x PBS, pH 7.2

Gene Information

• Gene Name: Thpo thrombopoietin [ Mus musculus (house mouse) ]
• Official Symbol: Thpo
• Synonyms: THPO; thrombopoietin; C-mpl ligand; megakaryocyte colony-stimulating factor; megakaryocyte growth and development factor; myeloproliferative leukemia virus oncogene ligand; Ml; Tpo; Mgdf; Tpo1; Tpo2; Tpo3; Tpo4; Mpllg
• Gene ID: 21832
• mRNA Refseq: NM_001173505
• Protein Refseq: NP_001166976
• UniProt ID: P40226