Active Recombinant Mouse Spint1 Protein, Fc-tagged

• Cat.No.: Spint1-866M
• Product Overview: Recombinant mouse Spint1 (NP_058603.2) (Met1-Glu443) was expressed with the Fc region of human IgG1 at the C-terminus.

Specification

• Species: Mouse
• Source: HEK293
• Tag: Fc
• Protein Length: 1-443 a.a.
• Predicted N Terminal: Glu 30
• Form: Lyophilized from sterile PBS, pH 7.4, 5%~8% trehalose and mannitol.
• Bio-activity: Measured by its ability to inhibit trypsin cleavage of a fluorogenic peptide substrate, Mca-Arg-Pro-Lys-Pro-Val-Glu-NVAL-Trp-Arg-Lys(DNP)-NH2. The IC50 value is< 1.5 nM.
• Molecular Mass: The recombinant mouse Spint1 consists 652 amino acids and predicts a molecular mass of 73.2 kDa.
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: >95 % as determined by SDS-PAGE.
• Stability: Samples are stable for up to twelve months from date of receipt at -70ºC.
• Storage: Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: Spint1 serine protease inhibitor, Kunitz type 1 [ Mus musculus ]
• Official Symbol: Spint1
• Synonyms: SPINT1; serine protease inhibitor, Kunitz type 1; kunitz-type protease inhibitor 1; hepatocyte growth factor activator inhibitor type 1; HAI-1
• Gene ID: 20732
• mRNA Refseq: NM_016907
• Protein Refseq: NP_058603
• Pathway: Transcriptional misregulation in cancer, organism-specific biosystem; Transcriptional misregulation in cancer, conserved biosystem
• Function: peptidase inhibitor activity; serine-type endopeptidase inhibitor activity