Recombinant Human SPINT1

• Cat.No.: SPINT1-29310TH
• Product Overview: Recombinant full length Human HGFA Inhibitor 1 with N-terminal proprietary tag. Predicted MW 82.5kDa.

Specification

• Species: Human
• Source: Wheat Germ
• Tag: Non
• Protein Length: 513 amino acids
• Description: The protein encoded by this gene is a member of the Kunitz family of serine protease inhibitors. The protein is a potent inhibitor specific for HGF activator and is thought to be involved in the regulation of the proteolytic activation of HGF in injured tissues. Alternative splicing results in multiple variants encoding different isoforms.
• Molecular Weight: 82.500kDa inclusive of tags
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: MAPARTMARARLAPAGIPAVALWLLCTLGLQGTQAGPPPA PPGLPAGADCLNSFTAGVPGFVLDTNASVSNGATFLESPT VRRGWDCVRACCTTQNCNLALVELQPDRGEDAIAACFLIN CLYEQNFVCKFAPREGFINYLTREVYRSYRQLRTQGFGGS GIPKAWAGIDLKVQPQEPLVLKDVENTDWRLLRGDTDVRV ERKDPNQVELWGLKEGTYLFQLTVTSSDHPEDTANVTVTV LSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVY GGCLGNKNNYLREEECILACRGVQGPSMERRHPVCSGTCQ PTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTSGF DELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHC ARFTYGGCYGNKNNFEEEQQCLESCRGISKKDVFGLRREI PIPSTGSVEMAVAVFLVICIVVVVAILGYCFFKNQRKDFH GHHHHPPPTPASSTVSTTEDTEHLVYNHTTRPL
• Sequence Similarities: Contains 2 BPTI/Kunitz inhibitor domains.Contains 1 LDL-receptor class A domain.Contains 1 MANSC domain.

Gene Information

• Gene Name: SPINT1 serine peptidase inhibitor, Kunitz type 1 [ Homo sapiens ]
• Official Symbol: SPINT1
• Synonyms: SPINT1; serine peptidase inhibitor, Kunitz type 1; serine protease inhibitor, Kunitz type 1; kunitz-type protease inhibitor 1; HAI; MANSC2
• Gene ID: 6692
• mRNA Refseq: NM_001032367
• Protein Refseq: NP_001027539
• MIM: 605123
• Uniprot ID: O43278
• Chromosome Location: 15q13.3
• Pathway: Transcriptional misregulation in cancers, organism-specific biosystem; Transcriptional misregulation in cancers, conserved biosystem
• Function: peptidase inhibitor activity; serine-type endopeptidase inhibitor activity