Active Recombinant Mouse Pf4 Protein

Cat.No. : Pf4-4803M
Product Overview : Purified recombinant protein of Mouse platelet factor 4 (Pf4 / PF-4) without tag was expressed in E. coli.
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Species : Mouse
Source : E.coli
Protein Length : Val30-Ser105
Description : Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation.
Bio-activity : The ED50 is 3-5 μg/ml, corresponding to a specific activity 2.0-3.3 × 10^2 units/mg, determined by a dose-dependent inhibition of human FGF-basic-dependent proliferation of human umbilical vein endothelial cells (HUVEC).
Molecular Mass : 8.2 kDa
Endotoxin : Less than 0.01 ng/μg protein as determined by the LAL method
Purity : > 98%, as determined by Coomassie stained SDS-PAGE.
Stability : Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Storage : Store at -80 centigrade.
Concentration : Protein formulated and vialed at >50 μg/mL in specified buffer
Storage Buffer : 1 x PBS
Gene Name Pf4 platelet factor 4 [ Mus musculus (house mouse) ]
Official Symbol Pf4
Synonyms PF4; platelet factor 4; PF-4; C-X-C motif chemokine 4; chemokine (C-X-C motif) ligand 4; Cxcl4; Scyb4
Gene ID 56744
mRNA Refseq NM_019932
Protein Refseq NP_064316
UniProt ID Q9Z126

Not For Human Consumption!

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