Active Recombinant Mouse Lgr6 Protein, C-Fc-tagged

• Cat.No.: Lgr6-06M
• Product Overview: Recombinant Mouse Lgr6 Fc Chimera Protein (Gly23-Ala567) with a Mouse IgG2A (Glu98-Lys330) Fc tag at C-terminus was expressed in Chinese Hamster Ovary cell line.

Specification

• Description: Predicted to enable G protein-coupled receptor activity and protein-hormone receptor activity. Acts upstream of or within bone regeneration. Predicted to be located in vesicle. Predicted to be active in extracellular matrix and extracellular space. Is expressed in 1st branchial arch; jaw; nasal process; oral region epithelium; and skin. Orthologous to human LGR6 (leucine rich repeat containing G protein-coupled receptor 6).
• Source: CHO
• Species: Mouse
• Tag: Fc
• Form: Disulfide-linked homodimer
• Bio-activity: Measured by its binding ability in a functional ELISA. When Recombinant Mouse R‑Spondin 3 is coated at 0.5 μg/mL, Recombinant Mouse Lgr6 Fc Chimera binds with an apparent Kd < 1.0 nM.
• Molecular Mass: Predicted Molecular Mass: 87.9 kDa (monomer)
  SDS-PAGE: 95-105 kDa, reducing conditions
• Protein length: Gly23-Ala567
• N-terminal Sequence Analysis: Gly23
• Endotoxin: <0.01 EU/μg of the protein by the LAL method.
• Purity: >95%, by SDS-PAGE with silver staining, under reducing conditions.
• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  12 months from date of receipt, -20 to -70 centigrade as supplied.
  1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
  3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution in PBS.
• Reconstitution: Reconstitute at 200 μg/mL in PBS.
• Shipping: The product is shipped at ambient temperature.

Gene Information

• Gene Name: Lgr6 leucine-rich repeat-containing G protein-coupled receptor 6 [ Mus musculus (house mouse) ]
• Official Symbol: Lgr6
• Synonyms: Lgr6; leucine-rich repeat-containing G protein-coupled receptor 6; D830026M09; A530037C04Rik; leucine-rich repeat-containing G-protein coupled receptor 6
• Gene ID: 329252
• mRNA Refseq: NM_001033409
• Protein Refseq: NP_001028581
• UniProt ID: Q3UVD5