Active Recombinant Mouse Kat2b, His-tagged

• Cat.No.: Kat2b-455M
• Product Overview: Mouse PCAF is fused to a His-tag.

Specification

• Description: PCAF functions as a histone acetyltransferase (HAT) to promote transcriptional activation. It has significant histone acetyltransferase activity with core histones H3 and H4, and also with nucleosome core particles.
• Source: Baculovirus infected Sf21 Cells
• Species: Mouse
• Tag: His
• Form: Liquid. In 50mM TRIS-HCl, pH 7.5, containing 100mM sodium chloride, 50mM imidazole, 0.2% NP-40 and 10% glycerol.
• Bio-activity: ~100-200ng are required for standard HAT assay.
• Purity: ≥95% (SDS-PAGE)
• Stability: Stable for at least 6 months after receipt when stored at -80°C.
• Storage: Short Term Storage: -20°C; Long Term Storage: -80°C. After opening, prepare aliquots and store at -80°C. Avoid freeze/thaw cycles.
• Concentration: Lot dependent (0.2-0.5mg/ml)

Gene Information

• Gene Name: Kat2b K(lysine) acetyltransferase 2B [ Mus musculus ]
• Official Symbol: Kat2b
• Synonyms: KAT2B; K(lysine) acetyltransferase 2B; histone acetyltransferase KAT2B; histone acetylase PCAF; p300/CBP-associated factor; lysine acetyltransferase 2B; histone acetyltransferase PCAF; Pcaf; p/CAF; AI461839; AW536563; A930006P13Rik
• Gene ID: 18519
• mRNA Refseq: NM_001190846
• Protein Refseq: NP_001177775
• Pathway: Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem; NOTCH1 Intracellular Domain Regulates Transcription, organism-specific biosystem; Notch signaling pathway, organism-specific biosystem; Notch signaling pathway, conserved biosystem
• Function: N-acetyltransferase activity; acetyltransferase activity; cyclin-dependent protein kinase inhibitor activity; histone acetyltransferase activity; histone deacetylase binding; lysine N-acetyltransferase activity; lysine N-acetyltransferase activity; protein binding; protein kinase binding; transcription coactivator activity; transcription coactivator activity; transcription cofactor activity; transcription factor binding; transferase activity; transferase activity, transferring acyl groups