Active Recombinant Mouse Interleukin 33, MIgG2a Fc-tagged, mutant

• Cat.No.: IL33-120M
• Product Overview: The extracellular domain of mouse IL-33 (NP_001158196.1)(Gln118-Ile266) is fused to the N-terminus of the Fc region of a mutant mouse IgG2a was expressed in CHO cell.

Specification

• Species: Mouse
• Source: CHO
• Tag: Fc
• Protein Length: 118-266 a.a.
• Description: IL33 (interleukin 33) is a protein-coding gene. Diseases associated with IL33 include allergic asthma, and endotheliitis, and among its related super-pathways are Cytosolic sensors of pathogen-associated DNA and Measles. GO annotations related to this gene include protein binding and cytokine activity.
• Form: Lyophilized from 0.2μm-filtered solution in PBS.
• Bio-activity: Measured in a cell proliferation assay.
• Molecular Mass: 43KDa (monomer)
• AA Sequence: Gln118-Ile266
• Endotoxin: <0.06 eu/μg="" as="" determined="" by="" lal="" test.="">
• Purity: >98%, by SDS-PAGE under reducing conditions.
• Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
• Reconstitution: Reconstitute at 100μg/ml in sterile PBS.
• Warning: Avoid freeze/thaw cycles.

Gene Information

• Gene Name: Il33 interleukin 33 [ Mus musculus ]
• Official Symbol: IL33
• Synonyms: IL33; interleukin 33; interleukin-33; nuclear factor from high endothelial venules; Il-33; Il1f11; NF-HEV; 9230117N10Rik
• Gene ID: 77125
• mRNA Refseq: NM_001164724
• Protein Refseq: NP_001158196
• Pathway: Cytosolic DNA-sensing pathway, organism-specific biosystem; Cytosolic DNA-sensing pathway, conserved biosystem; Influenza A, organism-specific biosystem; Influenza A, conserved biosystem
• Function: cytokine activity; cytokine activity; cytokine activity