Active Recombinant Mouse Interleukin 17A, MIgG2a Fc-tagged
Cat.No. : | IL17A-001H |
Product Overview : | The extracellular domain of mouse IL-17 (NP_034682.1)(Met1-Leu142) is fused to the N-terminus of the Fc region of a mouse IgG2a was expressed in CHO cell. |
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Species : | Mouse |
Source : | CHO |
Tag : | Fc |
Protein Length : | 1-142 a.a. |
Description : | The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokineregulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate theexpression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO).High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoidarthritis, psoriasis and multiple sclerosis. |
Form : | Lyophilized from 0.2μm-filtered solution in PBS. |
Bio-activity : | Measured by its ability to induce IL-6 secretion . |
Molecular Mass : | 39KDa (monomer) |
AA Sequence : | Met1-Leu142 |
Endotoxin : | <0.06 eu/μg="" as="" determined="" by="" lal="" test.="">0.06> |
Purity : | >98%, by SDS-PAGE under reducing conditions. |
Stability : | Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
Reconstitution : | Reconstitute at 100μg/ml in sterile PBS. |
Warning : | Avoid freeze/thaw cycles. |
Gene Name | Il17a interleukin 17A [ Mus musculus ] |
Official Symbol | IL17A |
Synonyms | IL17A; interleukin 17A; interleukin-17A; cytotoxic T-lymphocyte-associated antigen 8; Il17; Ctla8; IL-17; Ctla-8; IL-17A; |
Gene ID | 16171 |
mRNA Refseq | NM_010552 |
Protein Refseq | NP_034682 |
Pathway | Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Rheumatoid arthritis, organism-specific biosystem; Rheumatoid arthritis, conserved biosystem; |
Function | cytokine activity; |
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◆ Cell & Tissue Lysates | ||
IL17A-001HCL | Recombinant Human IL17A cell lysate | +Inquiry |
Not For Human Consumption!
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