Active Recombinant Mouse Ces1g Protein (His19-Leu565), C-6×His tagged

• Cat.No.: Ces1g-14M
• Product Overview: Recombinant Mouse Carboxylesterase 1/CES1 Protein (His19-Leu565) with a C-terminal 6-His tag was expressed in Mouse myeloma cell line.

Specification

• Species: Mouse
• Source: NS0
• Tag: His
• Protein Length: His19-Leu565
• Description: This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. The expression and activity of this gene is age-related but independent of growth hormone level. This gene is clustered with Ces7 and Ces3 on chromosome 8.
• Bio-activity: Measured by its ability to hydrolyze p-nitrophenylacetate. The specific activity is >330 pmol/min/μg, as measured under the described conditions.
• Molecular Mass: Predicted Molecular Mass: 62 kDa
  SDS-PAGE: 55-60 kDa, reducing conditions
• N-terminal Sequence Analysis: His19
• Endotoxin: < 0.01 EU/μg of the protein by the LAL method.
• Purity: > 90%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie Blue stain at 5 μg per lane
• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  6 months from date of receipt, -20 to -70 centigrade as supplied.
  3 months, -20 to -70 centigrade under sterile conditions after opening.
• Storage Buffer: Supplied as a 0.2 μm filtered solution in Tris and NaCl.
• Shipping: The product is shipped with polar packs.

Gene Information

• Gene Name: Ces1g carboxylesterase 1G [ Mus musculus (house mouse) ]
• Official Symbol: Ces1g
• Synonyms: Ces1g; carboxylesterase 1G; liver carboxylesterase 1; ES-x; acyl-coenzyme A:cholesterol acyltransferase; carboxylesterase 1; cholesteryl ester hydrolase; EC 3.1.1.1; EC 3.1.1.13; CEH; Ces1; Ces-1; Ses-1
• Gene ID: 12623
• mRNA Refseq: NM_021456
• Protein Refseq: NP_067431
• UniProt ID: Q8VCC2