Active Recombinant Mouse Asgr2 Protein, His-tagged

• Cat.No.: Asgr2-3665M
• Product Overview: Recombinant mouse Asgr2 Protein with His tag was expressed in Mouse myeloma cell line.

Specification

• Description: This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
• Source: Mammalian cells
• Species: Mouse
• Tag: His
• Bio-activity: Measured by its binding ability in a functional ELISA. rmASGPR1 immobilized at 2.5 μg/mL (100 μL/well) on a Mouse Anti-polyHistidine Monoclonal Antibody coated plate can bind biotinylated beta -Gal-NAc-PAA with a linear range of 2-150 ng/mL.
• Molecular Mass: 27 kDa
• N-terminal Sequence Analysis: His
• Endotoxin: <1.0 EU per 1 μg of the protein by the LAL method.
• Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  12 months from date of receipt, -20 to -70 centigrade as supplied.
  1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
  3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution in PBS.
• Reconstitution: Reconstitute at 250 μg/mL in sterile PBS.

Gene Information

• Gene Name: Asgr2 asialoglycoprotein receptor 2 [ Mus musculus (house mouse) ]
• Official Symbol: Asgr2
• Synonyms: Asgr2; asialoglycoprotein receptor 2; Asgr; HL-2; ASGPR2; Asgr-2; asialoglycoprotein receptor 2; hepatic lectin 2
• Gene ID: 11890
• mRNA Refseq: NM_007493
• Protein Refseq: NP_031519
• UniProt ID: P24721