Active Recombinant Mouse Artemin
Cat.No. : | Artn-578M |
Product Overview : | Recombinant Mouse Artnprotein was expressed in E. coli. Ala112-Gly224. |
- Specification
- Gene Information
- Related Products
- Download
Species : | Mouse |
Source : | E.coli |
Tag : | Non |
Protein Length : | 112-224 a.a. |
Description : | Artn is a member ofthe Glia CellDerived Neurotrophic factor (GDNF) family ligands, which includeGDNF, Persephin, Artn, and Neurturin. GDNF family ligands are distant membersof the Transforming Growth Factor β (TGFβ) superfamily. Similar to other TGFβfamily proteins, Artn is synthesized as a large precursor protein that iscleaved at the dibasic cleavage site (RXXR) to release the carboxy terminal domain. |
Form : | Lyophilized from a0.2 μm filtered solution in Acetonitrile and TFA with BSA as a carrierprotein. |
N-terminalSequence : | Ala112 |
Molecular Weight : | 12 kDa (monomer) |
Activity : | Measured in a cellproliferation assay using SHSY5Y human neuroblastoma cells. The ED50for this effect is typically 2-8 ng/mL. Measured by its binding ability in afunctional ELISA. Immobilized recombinant human GFRα3 Fc Chimera at 2 μg/mL(100 μL/well) can bind Recombinant Mouse Artemin with a linear range of 0.08-10ng/mL. |
Endotoxin Level : | < 1.0EU per 1 μg of the protein by the LAL method. |
Purity : | > 97%, by SDSPAGEunder reducing conditions and visualized by silver stain. |
Reconstitution : | 100 μg/mL in sterile4 mM HCI containing at least 0.1% human or bovine serum albumin. |
Storage : | Use a manualdefrost freezer and avoid repeated freeze-thaw cycles. 12 months from date ofreceipt, -20 to -70°C as supplied. 1 month, 2 to 8°C under sterile conditionsafter reconstitution. 3 months, -20 to -70°C under sterile conditions after reconstitution. |
Gene Name | Artn artemin [ Mus musculus] |
Official Symbol | Artn |
Synonyms | Artn; artemin;neublastin |
Gene ID | 11876 |
mRNA Refseq | NM_009711 |
Protein Refseq | NP_033841 |
Chromosome Location | 4; 4 D1 |
Pathway | Axon guidance;Developmental Biology; NCAM signaling for neurite out-growth; NCAM1interactions |
Function | glial cellline-derived neurotrophic factor receptor binding; growth factor activity;protein binding; receptor binding |
◆ Recombinant Proteins | ||
ARTN-12H | Recombinant Human Artemin | +Inquiry |
ARTN-703H | Recombinant Human ARTN Protein | +Inquiry |
ARTN-1691H | Recombinant Human ARTN protein, His & GST-tagged | +Inquiry |
ARTN-006H | Active Recombinant Human ARTN Protein | +Inquiry |
Artn-1692M | Recombinant Mouse Artn protein, His-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
ARTN-134HCL | Recombinant Human ARTN cell lysate | +Inquiry |
Not For Human Consumption!
Inquiry
- Reviews
- Q&As
Ask a Question for All Artn Products
Required fields are marked with *
My Review for All Artn Products
Required fields are marked with *
0
Inquiry Basket