Active Recombinant Mouse Acvr1b Protein, Fc-tagged

• Cat.No.: Acvr1b-975M
• Product Overview: Recombinant mouse Acvr1b (NP_031421.1) (Met1-Glu126) was expressed with the Fc region of human IgG1 at the C-terminus.

Specification

• Species: Mouse
• Source: HEK293
• Tag: Fc
• ProteinLength: 1-126 a.a.
• Predicted N Terminal: Ser
• Form: Lyophilized from sterile PBS, pH 7.4, 5%~8% trehalose and mannitol.
• Bio-activity: Measured by its ability to bind with rat TDGF1-His in a functional ELISA.
• Molecular Mass: The recombinant mouse Acvr1b consists 344 amino acids and predicts a molecular mass of 38.4 kDa.
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: >95 % as determined by SDS-PAGE.
• Stability: Samples are stable for up to twelve months from date of receipt at -70ºC.
• Storage: Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: Acvr1b activin A receptor, type 1B [ Mus musculus ]
• Official Symbol: Acvr1b
• Synonyms: ACVR1B; activin A receptor, type 1B; activin receptor type-1B; ALK-4; activin receptor type IB; activin receptor-like kinase 4; serine/threonine-protein kinase receptor R2; Alk4; SKR2; ActRIB; ActR-IB; Acvrlk4; 6820432J04
• Gene ID: 11479
• mRNA Refseq: NM_007395
• Protein Refseq: NP_031421
• Pathway: Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; MAPK signaling pathway, organism-specific biosystem; PluriNetWork, organism-specific biosystem
• Function: ATP binding; SMAD binding; activin binding; activin receptor activity, type I; inhibin binding; kinase activity; metal ion binding; nucleotide binding; protein binding; protein kinase activity; protein serine/threonine kinase activity; protein serine/thre