Active Recombinant Human VWF protein, Met/His-tagged
Cat.No. : | VWF-2712H |
Product Overview : | Recombinant Human VWF(Asp1498-Val1665) fused with Met/His tag at N-terminal was expressed in E. coli. |
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Source : | E. coli |
Species : | Human |
Tag : | His |
Predicted N Terminal : | Met |
Form : | Supplied as a 0.2 μm filtered solution in Tris, NaCl and Glycerol. |
Bio-activity : | Measured by its ability to be used as a protein substrate for ADAMTS13. >50% of rhvWF-A2 is cleaved as measured under the described conditions. |
Molecular Mass : | Predicted Molecular Mass: 20 kDa;SDS-PAGE: 18 kDa, reducing conditions. |
Endotoxin : | <1.0 EU per 1 μg of the protein by the LAL method. |
Purity : | >90%, by SDS-PAGE under reducing conditions and visualized by silver stain |
Storage : | Avoid repeated freeze-thaw cycles.6 months from date of receipt, -20 to -70 centigrade as supplied.3 months, -20 to -70 centigrade under sterile conditions after opening. |
Protein length : | 1498-1665 a.a. |
Gene Name | VWF von Willebrand factor [ Homo sapiens ] |
Official Symbol | VWF |
Synonyms | VWF; von Willebrand factor; F8VWF; coagulation factor VIII VWF; VWD; |
Gene ID | 7450 |
mRNA Refseq | NM_000552 |
Protein Refseq | NP_000543 |
MIM | 613160 |
UniProt ID | P04275 |
Chromosome Location | 12p13.3 |
Pathway | Blood Clotting Cascade, organism-specific biosystem; Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; ECM-receptor interaction, organism-specific biosystem; ECM-receptor interaction, conserved biosystem; Focal Adhesion, organism-specific biosystem; |
Function | chaperone binding; collagen binding; glycoprotein binding; immunoglobulin binding; integrin binding; protease binding; protease binding; protein N-terminus binding; protein binding; protein homodimerization activity; |
Not For Human Consumption!
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