Active Recombinant Human VRK1, GST-tagged

Description :	VRK1 is a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. VRK1 is widely expressed in human tissues and actively dividing cells, such as those in testis, leukocytes, fetal liver and carcinomas. VRK1 regulate cell proliferation and phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN. The spinal muscular atrophy with pontocerebellar hypoplasia is caused by a mutation in the VRK1 gene.
Source :	Sf9 Cells
Species :	Human
Tag :	GST
Form :	Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Bio-activity :	2 nmol/min/mg
Molecular Mass :	~71 kDa
Protein length :	Full length
Purity :	>95%
Applications :	Kinase Assay, Western Blot
Storage :	Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles.
Concentration :	0.1μg/μl

Gene Name	VRK1 vaccinia related kinase 1 [ Homo sapiens ]
Official Symbol	VRK1
Synonyms	VRK1; vaccinia related kinase 1; serine/threonine-protein kinase VRK1; vaccinia-related kinase 1; vaccinia virus B1R-related kinase 1; PCH1; MGC117401; MGC138280; MGC142070;
Gene ID	7443
mRNA Refseq	NM_003384
Protein Refseq	NP_003375
MIM	602168
UniProt ID	Q99986
Chromosome Location	14q32
Function	ATP binding; nucleotide binding; protein binding; protein serine/threonine kinase activity;