Active Recombinant Human USP10 Protein, GST-tagged

• Cat.No.: USP10-01H
• Product Overview: Recombinant human USP10 (154-798) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Description: Ubiquitin is a highly conserved protein that is covalently linked to other proteins to regulate their function and degradation. This gene encodes a member of the ubiquitin-specific protease family of cysteine proteases. The enzyme specifically cleaves ubiquitin from ubiquitin-conjugated protein substrates. The protein is found in the nucleus and cytoplasm. It functions as a co-factor of the DNA-bound androgen receptor complex, and is inhibited by a protein in the Ras-GTPase pathway. The human genome contains several pseudogenes similar to this gene. Several transcript variants, some protein-coding and others not protein-coding, have been found for this gene.
• Source: Insect cell
• Species: Human
• Tag: GST
• Molecular Mass: 125 kDa
• Purity: >90%
• Stability: One year at -70 centigrade from date of shipment.
• Storage: Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.1 μg/μL
• Storage Buffer: 50 mM Tris-HCl, pH7.5, 150 mM NaCl, 10 mM glutathione, 0.25 mM DTT, 0,1 mM EDTA, 0.2 mM PMSF, 25% glycerol.
• Protein length: 154-798 a.a.

Gene Information

• Gene Name: USP10 ubiquitin specific peptidase 10 [ Homo sapiens (human) ]
• Official Symbol: USP10
• Synonyms: USP10; ubiquitin specific peptidase 10; UBPO; ubiquitin carboxyl-terminal hydrolase 10; deubiquitinating enzyme 10; ubiquitin specific protease 10; ubiquitin thioesterase 10; ubiquitin thiolesterase 10; ubiquitin-specific-processing protease 10; EC 3.4.19.12
• Gene ID: 9100
• mRNA Refseq: NM_005153
• Protein Refseq: NP_005144
• MIM: 609818
• UniProt ID: Q14694