Active Recombinant Human TNFSF4 Protein, C-His-tagged

• Cat.No.: TNFSF4-21H
• Product Overview: Recombinant Human TNFSF4 Protein, fused to His-tag, was expressed in HEK293T.

Specification

• Description: This gene encodes a cytokine of the tumor necrosis factor (TNF) ligand family. The encoded protein functions in T cell antigen-presenting cell (APC) interactions and mediates adhesion of activated T cells to endothelial cells. Polymorphisms in this gene have been associated with Sjogren's syndrome and systemic lupus erythematosus. Alternative splicing results in multiple transcript variants.
• Source: HEK293T
• Species: Human
• Tag: His
• Form: Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol.
• Bio-activity: Measured by its binding ability in a functional ELISA with Human OX40/TNFRSF4.
• Molecular Mass: 16.2kDa
• Protein length: 139aa
• AA Sequence: QVSHRYPRIQ SIKVQFTEYK KEKGFILTSQ KEDEIMKVQN NSVIINCDGF YLISLKGYFS QEVNISLHYQ KDEEPLFQLK KVRSVNSLMV ASLTYKDKVY LNVTTDNTSL DDFHVNGGEL ILIHQNPGEF CVL
• N-terminal Sequence Analysis: 51-183aa
• Endotoxin: < 1 EU per 1ug of protein (determined by LAL method).
• Purity: > 90% by SDS-PAGE
• Applications: SDS-PAGE, Bioactivity
• Usage: For research use only. This product is not intended or approved for human, diagnostics or veterinary use.
• Storage: Can be stored at 2 centigrade to 8 centigrade for 1 week. For long term storage, aliquot and store at -20 centigrade to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 1mg/ml (determined by Bradford assay).

Gene Information

• Gene Name: TNFSF4 TNF superfamily member 4 [ Homo sapiens (human) ]
• Official Symbol: TNFSF4
• Synonyms: GP34; CD252; OX4OL; TXGP1; CD134L; OX-40L; TNLG2B
• Gene ID: 7292
• mRNA Refseq: NM_003326.5
• Protein Refseq: NP_003317.1
• MIM: 603594
• UniProt ID: P23510