Active Recombinant Human TGFB1 Protein, Animal Free

Specification
Gene Information
Related Products
Download

Description :	Transforming growth factor beta 1(TGF-β1) is one of three closely related mammalian members of the large TGF-β superfamily, TGF-β1, β2, and β3, signal through the same receptor and elicit similar biological responses. TGF-β1 is the most abundant isoform secreted by almost every cell type. TGF-β1 is a multifunctional cytokine that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGF-β1 and have specific receptors for it. TGF-β1 positively and negatively regulates many other growth factors. TGF-β1 plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts.
Source :	Human cells
Species :	Human
Bio-activity :	The activity was measured by its ability to inhibit the IL-4 induced proliferation in mouse HT-2 cells (BALB/c spleen activated by sheep erythrocytes in the presence of IL-2).
Molecular Mass :	25 kDa
Endotoxin :	<0.5 EU/ μg
Purity :	High Purity, >95% by SDS-PAGE
Stability :	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -80 centigrade under sterile conditions after reconstitution.
Storage Buffer :	Lyophilized from a 0.2 μm filtered solution in PBS without carrier protein
Reconstitution :	Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile 4 mM HCl containing at least 0.1% human or bovine serum albumin.

Gene Name	TGFB1 transforming growth factor, beta 1 [ Homo sapiens (human) ]
Official Symbol	TGFB1
Synonyms	TGFB1; transforming growth factor, beta 1; DPD1, TGFB; transforming growth factor beta-1; Camurati Engelmann disease; CED; TGFbeta; TGF-beta-1; TGF-beta 1 protein; latency-associated peptide; LAP; DPD1; TGFB;
Gene ID	7040
mRNA Refseq	NM_000660
Protein Refseq	NP_000651
MIM	190180
UniProt ID	P01137