Active Recombinant Human ST6GALNAC1 Protein (AA 36-600), N-6×His/GFP tagged

Description :	Glycosylation of proteins affects cell-cell interaction, interactions with the matrix, and the functions of intracellular molecules. ST6GALNAC1 transfers a sialic acid, N-acetylneuraminic acid (NeuAc), in an alpha-2,6 linkage to O-linked GalNAc residues. The cancer-associated sialyl-Tn (sTn) antigen is formed by ST6GALNAC1-catalyzed sialylation of GalNAc residues on mucins (Ikehara et al., 1999 [PubMed 10536037]; Sewell et al., 2006 [PubMed 16319059]).
Source :	HEK293
Species :	Human
Tag :	His&GFP
Bio-activity :	≥0.1 μmol/min/mg
Molecular Mass :	~90 kDa
Protein length :	AA 36-600
AA Sequence :	MRSCLWRCRHLSQGVQWSLLLAVLVFFLFALPSFIKEPQTKPSRHQRTENIKERSLQSLAKPKSQAPTRARRTTIYAEPVPENNALNTQTQPKAHTTGDRGKEANQAPPEEQDKVPHTAQRAAWKSPEKEKTMVNTLSPRGQDAGMASGRTEAQSWKSQDTKTTKGNGGQTRKLTASRTVSEKHQGKAATTAKTLIPKSQHRMLAPTGAVSTRTRQKGVTTAVIPPKEKKPQATPPPAPFQSPTTQRNQRLKAANFKSEPRWDFEEKYSFEIGGLQTTCPDSVKIKASKSLWLQKLFLPNLTLFLDSRHFNQSEWDRLEHFAPPFGFMELNYSLVQKVVTRFPPVPQQQLLLASLPAGSLRCITCAVVGNGGILNNSHIGQEIDSHDYVFRLSGALIKGYEQDVGTRTSFYGFTAFSLTQSLLILGNRGFKNVPLGKAQTPGSFSGSPAHGQVPVAAPRLSPIHEEQVSEV
Purity :	>95%, by SDS-PAGE under reducing conditions and visualized by Coomassie Blue stain.
Stability :	6 months if stored at -80 centigrade. Avoid repeated freeze thaws.
Concentration :	1 mg/mL
Storage Buffer :	Supplied as a 0.2 μm filtered solution in 20mM HEPES pH 7.0 and 100mM NaCl buffer, with 10% Glycerol.
Preservative :	0.05 % NaN3
Shipping :	This product is shipped as 0.2μm filtered product on dry ice.

Gene Name	ST6GALNAC1 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 [ Homo sapiens (human) ]
Official Symbol	ST6GALNAC1
Synonyms	ST6GALNAC1; ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1; sialyltransferase 7 ((alpha N acetylneuraminyl 2,3 beta galactosyl 1,3) N acetyl galactosaminide alpha 2,6 sialyltransferase) A , SIAT7A; alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1; ST6GalNAcI; SIAT7-A; ST6GalNAc I; sialyltransferase 7A; galNAc alpha-2,6-sialyltransferase I; GalNAc alpha-2, 6-sialyltransferase I, long form; sialyltransferase 7 ((alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl galactosaminide alpha-2,6-sialyltransferase) A; STYI; SIAT7A; HSY11339;
Gene ID	55808
mRNA Refseq	NM_018414
Protein Refseq	AAH22462
MIM	610138
UniProt ID	Q9NSC7

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