Active Recombinant Human SIGLEC6 Protein, Fc Chimera

• Cat.No.: SIGLEC6-876H
• Product Overview: Recombinant Human SIGLEC6 (Accession # NP_942142), fused with , was produced in Chinese Hamster Ovary cell line, CHO-derived.

Specification

• Species: Human
• Source: CHO
• Tag: Fc
• Predicted N Terminal: No results obtained: Gln27 predicted
• Form: Lyophilized from a 0.2 µm filtered solution in PBS.
• Bio-activity: Measured by its ability to bind biotinylated Neu5Ac alpha 2-6GalNAc alpha (sialyl-Tn). Patel, N. et al. (1999) The Journal of Biological Chemistry 274:22729.
• Molecular Mass: Recombinant Human SIGLEC6, Fc Chimera has a calculated MW of 60.3 kDa (monomer). In SDS-PAGE migrates as 80-95 kDa, reducing conditions.
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: SIGLEC6 sialic acid binding Ig-like lectin 6 [ Homo sapiens ]
• Official Symbol: SIGLEC6
• Synonyms: SIGLEC6; sialic acid binding Ig-like lectin 6; CD33L, CD33L1; sialic acid-binding Ig-like lectin 6; CD327; OB BP1; SIGLEC 6; CD33 antigen-like 1; obesity-binding protein 1; CD33L; OBBP1; CD33L1; CD33L2; CDW327
• Gene ID: 946
• mRNA Refseq: NM_001177547
• Protein Refseq: NP_001171018
• MIM: 604405
• UniProt ID: O43699
• Chromosome Location: 19q13.3