Active Recombinant Human PNMT protein, GST-tagged

Cat.No. : PNMT-197H
Product Overview : Recombinant Human PNMT fused with GST tag at N-terminal was expressed in Insect cells.
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Species : Human
Source : Insect Cells
Tag : GST
Description : Phenylethanolamine N-methyltransferase (PNMT) catalyzes the biosynthesis of adrenaline though methylation of phenylethanolamine. PNMT gene is reported to be involved in various human diseases including early-onset Alzheimer disease, Parkinson's disease, and multiple sclerosis. Expression of PNMT can be stimulated by nicotine.
Form : 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Bio-activity : 170 nmol/min/mg
Molecular Mass : 57 kDa
Purity : >95%
Applications : Methyltransferase Assay
Stability : 1 year at -70 centigrade from the date of shipment
Storage : Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Concentration : 0.1μg/μl
Gene Name PNMT phenylethanolamine N-methyltransferase [ Homo sapiens ]
Official Symbol PNMT
Synonyms PNMT; phenylethanolamine N-methyltransferase; PENT; phenylethanolamine N-methylase; noradrenaline N-methyltransferase; PNMTase; MGC34570;
Gene ID 5409
mRNA Refseq NM_002686
Protein Refseq NP_002677
MIM 171190
UniProt ID P11086
Chromosome Location 17q
Pathway Amine-derived hormones, organism-specific biosystem; Biogenic Amine Synthesis, organism-specific biosystem; Catecholamine biosynthesis, organism-specific biosystem; Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline, organism-specific biosystem;
Function methyltransferase activity; phenylethanolamine N-methyltransferase activity; transferase activity;

Not For Human Consumption!

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