Active Recombinant Human PNMT protein, GST-tagged
Cat.No. : | PNMT-197H |
Product Overview : | Recombinant Human PNMT fused with GST tag at N-terminal was expressed in Insect cells. |
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Species : | Human |
Source : | Insect Cells |
Tag : | GST |
Description : | Phenylethanolamine N-methyltransferase (PNMT) catalyzes the biosynthesis of adrenaline though methylation of phenylethanolamine. PNMT gene is reported to be involved in various human diseases including early-onset Alzheimer disease, Parkinson's disease, and multiple sclerosis. Expression of PNMT can be stimulated by nicotine. |
Form : | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Bio-activity : | 170 nmol/min/mg |
Molecular Mass : | 57 kDa |
Purity : | >95% |
Applications : | Methyltransferase Assay |
Stability : | 1 year at -70 centigrade from the date of shipment |
Storage : | Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Concentration : | 0.1μg/μl |
Gene Name | PNMT phenylethanolamine N-methyltransferase [ Homo sapiens ] |
Official Symbol | PNMT |
Synonyms | PNMT; phenylethanolamine N-methyltransferase; PENT; phenylethanolamine N-methylase; noradrenaline N-methyltransferase; PNMTase; MGC34570; |
Gene ID | 5409 |
mRNA Refseq | NM_002686 |
Protein Refseq | NP_002677 |
MIM | 171190 |
UniProt ID | P11086 |
Chromosome Location | 17q |
Pathway | Amine-derived hormones, organism-specific biosystem; Biogenic Amine Synthesis, organism-specific biosystem; Catecholamine biosynthesis, organism-specific biosystem; Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline, organism-specific biosystem; |
Function | methyltransferase activity; phenylethanolamine N-methyltransferase activity; transferase activity; |
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PNMT-197H | Active Recombinant Human PNMT protein, GST-tagged | +Inquiry |
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Not For Human Consumption!
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