Recombinant Human PNMT

• Cat.No.: PNMT-30072TH
• Product Overview: Recombinant full length Human PNMT; amino acids 1-282 , 30.8kDa.

Specification

• Description: The product of this gene catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline). The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production.
• Source: E. coli
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 10% Glycerol, 20mM Tris HCl, pH 8.0
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Store in the dark. Avoid repeated freeze / thaw cycles.
• Sequence Similarities: Belongs to the NNMT/PNMT/TEMT family.
• Tag: Non
• Protein length: 1-282 a.a.
• Full Length: Full L.

Gene Information

• Gene Name: PNMT phenylethanolamine N-methyltransferase [ Homo sapiens ]
• Official Symbol: PNMT
• Synonyms: PNMT; phenylethanolamine N-methyltransferase; PENT
• Gene ID: 5409
• mRNA Refseq: NM_002686
• Protein Refseq: NP_002677
• MIM: 171190
• Uniprot ID: P11086
• Chromosome Location: 17q
• Pathway: Amine-derived hormones, organism-specific biosystem; Biogenic Amine Synthesis, organism-specific biosystem; Catecholamine biosynthesis, organism-specific biosystem; Catecholamine biosynthesis, tyrosine => dopamine =>
• Function: methyltransferase activity; phenylethanolamine N-methyltransferase activity; transferase activity