Active Recombinant Human NRG1 Protein, His-tagged
Cat.No. : | NRG1-679H |
Product Overview : | Recombinant Human NRG1 (Accession # NP_039253) Met1-Glu296, Leu117-Glu296 & Ala162-Glu296, fused with a C-terminal 6-His tag, was produced in Spodoptera frugiperda, Sf 21 (baculovirus)-derived. |
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Species : | Human |
Source : | Sf21 Cells |
Tag : | His |
Protein Length : | Met1-Glu296, Leu117-Glu296 & Ala162-Glu296 |
Predicted N Terminal : | Met1, Leu117 & Ala162 |
Form : | Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein. |
Bio-activity : | Measured in a serum-free cell proliferation assay using MCF-7 human breast cancer cells. Karey, K.P. et al. (1988) Cancer Research 48:4083.The ED50 for this effect is typically 1 - 5 ng/mL. |
Molecular Mass : | Recombinant Human NRG1, His-tagged has a calculated MW of 33 kDa. In SDS-PAGE migrates as 25-45 kDa, reducing conditions. |
Purity : | >95%, by SDS-PAGE under reducing conditions and visualized by silver stain. |
Storage : | Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC). |
Gene Name | NRG1 neuregulin 1 [ Homo sapiens ] |
Official Symbol | NRG1 |
Synonyms | NRG1; neuregulin 1; HGL; pro-neuregulin-1, membrane-bound isoform; GGF; HRG; NDF; MSTP131; pro-NRG1; glial growth factor; neu differentiation factor; neuregulin 1 type IV beta 3; neuregulin 1 type IV beta 1a; sensory and motor neuron derived factor; heregulin, alpha (45kD, ERBB2 p185-activator); ARIA; GGF2; HRG1; HRGA; SMDF; MST131; |
Gene ID | 3084 |
mRNA Refseq | NM_001159995 |
Protein Refseq | NP_001153467 |
MIM | 142445 |
UniProt ID | Q02297 |
Chromosome Location | 8p21-p12 |
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Not For Human Consumption!
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