Active Recombinant Human NMNAT1, His-tagged

Description :	This gene encodes an enzyme which catalyzes a key step in the biosynthesis of the coenzyme NAD. The encoded protein is one of several nicotinamide nucleotide adenylyltransferases. Studies in Drosophila and mammalian neurons have shown the encoded protein can confer protection to damaged neurons. This protection requires enzymatic activity which increases NAD levels and activates a nuclear deacetylase which is the protective molecule. Pseudogenes of this gene are located on chromosomes 1, 3, 4, 14 and 15.
Source :	Sf 21 (baculovirus)
Species :	Human
Tag :	His
Predicted N Terminal :	Ser4
Form :	Supplied as a 0.2 µm filtered solution in Tris, NaCl, Glycerol and DTT.
Bio-activity :	Measured by the production of NAD+, which is converted to NADH by alcohol dehydrogenase. The specific activity is >2,500 pmol/min/µg.
Molecular Mass :	32 kDa
Endotoxin :	< 1.0 EU per 1 μg of the protein by the LAL method.
Purity :	>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage :	Avoid repeated freeze-thaw cycles. 6 months from date of receipt, -70 °C as supplied. 3 months, -70 °C under sterile conditions after opening.
Protein length :	1-279 a.a.

Gene Name	NMNAT1 nicotinamide nucleotide adenylyltransferase 1 [ Homo sapiens (human) ]
Official Symbol	NMNAT1
Synonyms	NMNAT1; LCA9; NMNAT; PNAT1; nicotinamide nucleotide adenylyltransferase 1; NMN adenylyltransferase 1; NaMN adenylyltransferase 1; pyridine nucleotide adenylyltransferase 1; nicotinate-nucleotide adenylyltransferase 1; EC 2.7.7.1; EC 2.7.7.18
Gene ID	64802
mRNA Refseq	NM_022787
Protein Refseq	NP_073624
MIM	608700
UniProt ID	Q9HAN9
Chromosome Location	1p36.22
Pathway	Metabolism; Metabolism of vitamins and cofactors; Metabolism of water-soluble vitamins and cofactors
Function	ATP binding; nicotinamide-nucleotide adenylyltransferase activity; nicotinamide-nucleotide adenylyltransferase activity