Active Recombinant Human MAP3K5, GST-tagged

• Cat.No.: MAP3K5-578H
• Product Overview: Recombinant Human MAP3K5 (Accession # NM_005923) amino acids 649 - 946, fused with an N-terminal GST tag, was produced in baculovirus in Sf 9 insect cells.

Specification

• Source: Sf 9 insect cells
• Species: Human
• Tag: GST
• Form: Supplied in 50 mM Tris HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 10 mM glutathione, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol.
• Bio-activity: The specific activity of ASK1 was determined to be 96 nmol/min/mg using a myelin basic protein (MBP) substrate
• Molecular Mass: In SDS-PAGE migrates as 60 kDa.
• Purity: The purity was determined to be >90% by densitometry
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
• Protein length: 649-946 a.a.

Gene Information

• Gene Name: MAP3K5 mitogen-activated protein kinase kinase kinase 5 [ Homo sapiens ]
• Official Symbol: MAP3K5
• Synonyms: MAP3K5; mitogen-activated protein kinase kinase kinase 5; MEKK5; apoptosis signal regulating kinase 1; ASK1; MAPKKK5; ASK-1; MEKK 5; MEK kinase 5; MAP/ERK kinase kinase 5; MAPK/ERK kinase kinase 5; apoptosis signal-regulating kinase 1
• Gene ID: 4217
• mRNA Refseq: NM_005923
• Protein Refseq: NP_005914
• MIM: 602448
• UniProt ID: Q99683
• Chromosome Location: 6q22.33