Active Recombinant Human MAP3K14 Protein, GST&His-tagged

• Cat.No.: MAP3K14-01H
• Product Overview: Human MAP3K14 (NM_003954, 1 a.a. - 947 a.a.) full-length recombinant protein with GST-His tag was expressed in Sf9 cells.

Specification

• Species: Human
• Source: Insect Cells
• Tag: GST&His
• Description: This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor.
• Form: Liquid
• Bio-activity: 1 pmol/μg x min
• Molecular Mass: 133.437
• Applications: Functional Study
  SDS-PAGE
• Stability: Aliquot to avoid repeated freezing and thawing.
• Storage: Store at -80 centigrade.
• Concentration: 0.114 μg/μL
• Storage Buffer: In 50 mM Hepes, 100 mM NaCl, pH 7.5. (5 mM DTT, 15 mM reduced glutathione, 20% glycerol)

Gene Information

• Gene Name: MAP3K14 mitogen-activated protein kinase kinase kinase 14 [ Homo sapiens (human) ]
• Official Symbol: MAP3K14
• Synonyms: MAP3K14; mitogen-activated protein kinase kinase kinase 14; HS; NIK; HSNIK; FTDCR1B; mitogen-activated protein kinase kinase kinase 14; NF-kappa-beta-inducing kinase; serine/threonine-protein kinase NIK; EC 2.7.11.25
• Gene ID: 9020
• mRNA Refseq: NM_003954
• Protein Refseq: NP_003945
• MIM: 604655
• UniProt ID: Q99558