Active Recombinant Human MAOA Protein

• Cat.No.: MAOA-108H
• Product Overview: Recombinant human MAOA protein without tag was expressed in insect cells.

Specification

• Species: Human
• Source: Insect cells
• Description: This gene is one of two neighboring gene family members that encode mitochondrial enzymes which catalyze the oxidative deamination of amines, such as dopamine, norepinephrine, and serotonin. Mutation of this gene results in Brunner syndrome. This gene has also been associated with a variety of other psychiatric disorders, including antisocial behavior. Alternatively spliced transcript variants encoding multiple isoforms have been observed.
• Bio-activity: Activity Data(Unless otherwise stated, all assays are carried out at 37 centigrade in 90 mM potassium phosphate (pH 7.4))
  Substrate: Kynuramine (4-hydroxyquinoline formation)
  Linear with time up to: 30 min(Determined at 20 μM substrate, using a protein concentration of 5 μg/ml)
  Linear with protein up to: 20 μg/ml(Determined at 20 μM substrate, using an incubation time of 10 min)
  Vmax: 121 nmol/min/mg protein
  Km: 41 μM
• Usage: For laboratory (research) purposes only
• Storage: Store at -80 centigrade. Avoid frequent temperature changes. Thaw on ice.
• Concentration: Protein Concentration: 5 mg/ml
• Storage Buffer: 10 mM sodium phosphate (pH 7.4), 140 mM sodium chloride, 20% (v/v) glycerol

Gene Information

• Gene Name: MAOA monoamine oxidase A [ Homo sapiens (human) ]
• Official Symbol: MAOA
• Synonyms: MAOA; monoamine oxidase A; BRNRS; MAO-A; amine oxidase [flavin-containing] A; monoamine oxidase type A
• Gene ID: 4128
• mRNA Refseq: NM_000240
• Protein Refseq: NP_000231
• MIM: 309850
• UniProt ID: P21397