Active Recombinant Human KSR2 Mutant (R676S), GST-tagged
Cat.No. : | KSR2-83H |
Product Overview : | Recombinant human KSR2 (R676S) (554-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
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Species : | Human |
Source : | Sf9 Cells |
Tag : | GST |
Protein Length : | 554-end a.a. |
Description : | KSR2 or kinase suppressor of Ras 2 specifically regulates the activity of MEKK3 and COT but not other members of the MAP3K family. KSR interacts with a regulatory Raf molecule in cis to induce a conformational switch of MEK, facilitating MEK"s phosphorylation by a separate catalytic Raf molecule in trans. |
Form : | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Bio-activity : | The specific activity was determined to be 48 nmol/min/mg |
Molecular Mass : | ~72 kDa |
Purity : | >70% by densitometry. |
Applications : | Kinase Assay |
Storage : | Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Concentration : | 0.1 μg/μl |
Gene Name | KSR2 kinase suppressor of ras 2 [ Homo sapiens ] |
Official Symbol | KSR2 |
Synonyms | KSR2; kinase suppressor of ras 2; kinase suppressor of Ras 2; FLJ25965; |
Gene ID | 283455 |
mRNA Refseq | NM_173598 |
Protein Refseq | NP_775869 |
MIM | 610737 |
UniProt ID | Q6VAB6 |
Chromosome Location | 12q24.22-q24.23 |
Function | ATP binding; metal ion binding; protein serine/threonine kinase activity; transferase activity, transferring phosphorus-containing groups; |
◆ Recombinant Proteins | ||
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KSR2-7267Z | Recombinant Zebrafish KSR2 | +Inquiry |
KSR2-83H | Active Recombinant Human KSR2 Mutant (R676S), GST-tagged | +Inquiry |
KSR2-82H | Active Recombinant Human KSR2, GST-tagged | +Inquiry |
KSR2-4793H | Recombinant Human KSR2 Protein, GST-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
KSR2-963HCL | Recombinant Human KSR2 cell lysate | +Inquiry |
Not For Human Consumption!
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