KSR2
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Official Full Name
kinase suppressor of ras 2 -
Synonyms
KSR2;kinase suppressor of ras 2;FLJ25965;hKSR 2;hKSR2;KSR 2;OTTHUMP00000239951
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| KSR2-82H |
Active Recombinant Human KSR2, GST-tagged
|
Sf9 Insect Cell | Human | GST | 554-end a.a. |
|
| KSR2-83H |
Active Recombinant Human KSR2 Mutant (R676S), GST-tagged
|
Sf9 Insect Cell | Human | GST | 554-end a.a. |
|
| KSR2-7267Z | Recombinant Zebrafish KSR2 | Mammalian Cell | Zebrafish | His |
|
|
| KSR2-963HCL | Recombinant Human KSR2 cell lysate | Human | Non |
|
||
| KSR2-4793H | Recombinant Human KSR2 Protein, GST-tagged | Wheat Germ | Human | GST |
|
|
| KSR2-5839HF | Recombinant Full Length Human KSR2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 829 amino acids |
|
Involved Pathway
KSR2 involved in several pathways and played different roles in them. We selected most pathways KSR2 participated on our site, such as Ras signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with KSR2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ras signaling pathway | CALML3,KIT,ANGPT4,PIK3R5,FASLG,Fgf15,GNB2,PLD2,SHC1,FGF1 |
Protein Function
KSR2 has several biochemical functions, for example, ATP binding,metal ion binding,protein serine/threonine kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KSR2 itself. We selected most functions KSR2 had, and list some proteins which have the same functions with KSR2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | PSMC6,DNAH14,MYH15,SCN8A,PRKCB,STK33,TEP1,PSMC4,ZAP70,ERN1 |
| metal ion binding | TGFBR2,ZNF624,TRIM27,GMPR2,ZNRF2B,ZNF223,DPEP2,CCDC71L,KAT6A,ARFGAP1 |
| protein serine/threonine kinase activity | BMPR1AB,MAP2K1,NEK3,CDK15,CPNE3,ALPK2,MAPK12B,CDK12,LATS2,MLKL |
Interacting Protein
KSR2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KSR2 here. Most of them are supplied by our site. Hope this information will be useful for your research of KSR2.
b4dyc6_human;FKBP6;HSP90AA1;HSP90AB1;BRAF;FKBP5;CDC37;HSP90AB1;q96be0_human;PPP5C
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References
- Zawistowski, JS; Nakamura, K; et al. MicroRNA 9-3p Targets beta(1) Integrin To Sensitize Claudin-Low Breast Cancer Cells to MEK Inhibition. MOLECULAR AND CELLULAR BIOLOGY 33:2260-2274(2013).
- Kaneda, A; Fujita, T; et al. Activation of Bmp2-Smad1 Signal and Its Regulation by Coordinated Alteration of H3K27 Trimethylation in Ras-Induced Senescence. PLOS GENETICS 7:-(2011).
