Active Recombinant Human IL10RA protein

Source :	HEK293
Species :	Human
Predicted N Terminal :	His22
Form :	Lyophilized from a 0.2 μm filtered solution in PBS.
Bio-activity :	Measured by its ability to inhibit IL-10-dependent proliferation of MC/9‑2 mouse mast cells. Thompson-Snipes, L. et al. (1991) J. Exp. Med. 173:507. The ED50 for this effect is typically 0.05‑0.25 µg/mL in the presence of 2 ng/mL of Recombinant Human IL‑10.
Molecular Mass :	Predicted Molecular Mass: 24 kDa;SDS-PAGE: 38-52 kDa, reducing conditions
Endotoxin :	<0.10 EU per 1 μg of the protein by the LAL method.
Purity :	>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
Storage :	Avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 centigrade as supplied.1 month, 2 to 8 centigrade under sterile conditions after reconstitution.3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Reconstitution :	Reconstitute at 100 μg/mL in PBS.
Tag :	Non
Protein length :	22-235 a.a.

Gene Name	IL10RA interleukin 10 receptor, alpha [ Homo sapiens ]
Official Symbol	IL10RA
Synonyms	IL10RA; interleukin 10 receptor, alpha; IL10R; interleukin-10 receptor subunit alpha; CD210; CD210a; CDW210A; HIL 10R; IL-10RA; IL-10R subunit 1; IL-10R subunit alpha; IL-10 receptor subunit alpha; interleukin-10 receptor subunit 1; interleukin-10 receptor alpha chain; HIL-10R; IL-10R1;
Gene ID	3587
mRNA Refseq	NM_001558
Protein Refseq	NP_001549
MIM	146933
UniProt ID	Q13651
Chromosome Location	11q23
Pathway	Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Jak-STAT signaling pathway, organism-specific biosystem; Jak-STAT signaling pathway, conserved biosystem; Toxoplasmosis, organism-specific biosystem; Toxoplasmosis, conserved biosystem; Tuberculosis, organism-specific biosystem;
Function	interleukin-10 receptor activity; protein binding; receptor activity; signal transducer activity;