Active Recombinant Human FGF17 Protein

• Cat.No.: FGF17-030H
• Product Overview: The mature recombinant human FGF-17 protein consists of 184 amino acids (23-216) without tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Protein Length: 23-216 a.a.
• Description: This gene encodes a member of the fibroblast growth factor (FGF) family. Member of the FGF family possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is expressed during embryogenesis and in the adult cerebellum and cortex and may be essential for vascular growth and normal brain development. Mutations in this gene are the cause of hypogonadotropic hypogonadism 20 with or without anosmia. Alternate splicing results in multiple transcript variants.
• Bio-activity: Measured in a cell proliferation assay using NR6R-3T3 mouse fibroblast cells. The ED50 for this effect is 100-500 ng/mL, in the presence of 1 μg/mL heparin.
• Molecular Mass: 22.6 kDa
• Product-Related Proteins: 23-216
• Endotoxin: < 0.1 EU/μg of the protein as determined by the LAL method
• Purity: > 95 % as determined by SDS-PAGE
• Storage: At -80 centigrade. Avoid repeated freeze-thaw cycles.
• Storage Buffer: PBS

Gene Information

• Gene Name: FGF17 fibroblast growth factor 17 [ Homo sapiens (human) ]
• Official Symbol: FGF17
• Synonyms: FGF17; fibroblast growth factor 17; HH20; FGF-13; FGF-17; This gene encodes a member of the fibroblast growth factor (FGF) family. Member of the FGF family possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is expressed during embryogenesis and in the adult cerebellum and cortex and may be essential for vascular growth and normal brain development. Mutations in this gene are the cause of hypogonadotropic hypogonadism 20 with or without anosmia. Alternate splicing results in multiple transcript variants.
• Gene ID: 8822
• mRNA Refseq: NM_003867
• Protein Refseq: NP_003858
• MIM: 603725
• UniProt ID: O60258